发明授权
- 专利标题: Prostaglandin intermediates
- 专利标题(中): 前列腺素中间体
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申请号: US218427申请日: 1988-07-11
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公开(公告)号: US4866205A公开(公告)日: 1989-09-12
- 发明人: David L. Coffen , George W. Holland , W. Harry Mandeville , Perry Rosen , Frederick Wong
- 申请人: David L. Coffen , George W. Holland , W. Harry Mandeville , Perry Rosen , Frederick Wong
- 申请人地址: NJ Nutley NJ Nutley
- 专利权人: Hoffman-La Roche Inc.,Hoffman-La Roche Inc.
- 当前专利权人: Hoffman-La Roche Inc.,Hoffman-La Roche Inc.
- 当前专利权人地址: NJ Nutley NJ Nutley
- 主分类号: C07C405/00
- IPC分类号: C07C405/00 ; C07D307/935
摘要:
New optically active intermediates and processes thereto are provided for use in synthesizing therapeutically active prostaglandins of the formula: ##STR1## wherein R.sup.1 is hydrogen or lower alkyl; from a compound of the formula: ##STR2## wherein R.sup.1 is as above and R.sup.2 is hydrogen or a carboxy blocking group convertible to an acid by hydrolysis.
公开/授权文献
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