A vaginal drape having a substantially frustoconical configuration, and a perimeter expandable along the length thereof. The drape is adapted to be secured about the cervix uteri of a human female. The vaginal drape can be used alone or in cooperation with an insertion unit or a kit for conducting medical and/or surgical procedures on the uterus. The drape provides an aseptic region while a medical procedure is being performed on the uterus through the vaginal canal.