发明授权
US4868188A 4-(Benzisothiazol-3-yl)phenoxyacetic acid 1',1'-dioxides as diuretics
失效
4-(苯并异噻唑-3-基)苯氧基乙酸1',1'-二氧化物作为利尿剂
- 专利标题: 4-(Benzisothiazol-3-yl)phenoxyacetic acid 1',1'-dioxides as diuretics
- 专利标题(中): 4-(苯并异噻唑-3-基)苯氧基乙酸1',1'-二氧化物作为利尿剂
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申请号: US439098申请日: 1982-11-03
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公开(公告)号: US4868188A公开(公告)日: 1989-09-19
- 发明人: Gregory M. Shutske
- 申请人: Gregory M. Shutske
- 申请人地址: NJ Somerville
- 专利权人: Hoechst-Roussel Pharmaceuticals, Inc.
- 当前专利权人: Hoechst-Roussel Pharmaceuticals, Inc.
- 当前专利权人地址: NJ Somerville
- 主分类号: A61K31/425
- IPC分类号: A61K31/425 ; A61K31/428 ; A61P7/10 ; C07C45/46 ; C07C49/84 ; C07D275/04 ; C07D275/06
摘要:
Novel 4-(benzisothiazol-3-yl)phenoxyacetic acid 1',1'-dioxides of the formula ##STR1## where X is hydrogen, halogen or loweralkyl; R.sub.1 is hydrogen or loweralkyl; R.sub.2 and R.sub.3 are each independently Cl, Br or CH.sub.3, and related compounds, methods for preparing same and methods of treatment by administering compositions containing such a compound are described. These compounds are useful as diuretics.
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