A pipette device comprises a vertical housing, a cylinder member disposed at least in the lower section in the housing and urged upwardly so that the cylinder member is vertically slidable in the housing, a piston member urged upwardly and having a lower end portion vertically slidable in the cylinder member, and an engagement member for transmitting the downward movement of the piston member to the cylinder member. The engagement member engages the piston member with the cylinder member when the piston member moves down to an engagement position lower by a predetermined distance from the top position of the piston memer along the cylinder member, whereby the cylinder member is moved vertically together with the piston member against an upward urging force in the housing when the piston member is moved vertically between the engagement position and a position lower than the engagement position.