发明授权
- 专利标题： Mitomycin derivatives
- 专利标题（中）： 丝裂霉素衍生物
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申请号： US173219申请日： 1988-03-25
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公开(公告)号： US4880825A公开(公告)日： 1989-11-14
- 发明人: Masaji Kasai , Yutaka Kanda , Motomichi Kono , Yutaka Saito , Makoto Morimoto , Tadashi Ashizawa
- 申请人： Masaji Kasai , Yutaka Kanda , Motomichi Kono , Yutaka Saito , Makoto Morimoto , Tadashi Ashizawa
- 申请人地址： JPX Tokyo
- 专利权人： Kyowa Hakko Kogyo Kabushiki Kaisha
- 当前专利权人： Kyowa Hakko Kogyo Kabushiki Kaisha
- 当前专利权人地址： JPX Tokyo
- 优先权： JPX62-71115 19870325
- 主分类号： C07D491/22
- IPC分类号： C07D491/22
摘要：
Mitomycin derivatives having potent anti-tumor activity having the formula: ##STR1## wherein one of R.sub.1 and R.sub.2 represents carbamoyloxymethyl and the other represents hydrogen or R.sub.1 and R.sub.2 are bonded together to form methylene;X is hydrogen or halogen;Y is hydrogen or methyl;Z is hydrogen, methyl or acyl; andn is an integer of 2 or 3.
公开/授权文献
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