发明授权
US4883669A Transdermal absorption dosage unit for estradiol and other estrogenic
steroids and process for administration
失效
雌二醇和其他雌激素类固醇的经皮吸收剂量单位和给药方法
- 专利标题: Transdermal absorption dosage unit for estradiol and other estrogenic steroids and process for administration
- 专利标题(中): 雌二醇和其他雌激素类固醇的经皮吸收剂量单位和给药方法
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申请号: US868709申请日: 1986-05-30
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公开(公告)号: US4883669A公开(公告)日: 1989-11-28
- 发明人: Yie W. Chien , Chia-Shun Lee , Kirti H. Valia , Te-Yen Chien
- 申请人: Yie W. Chien , Chia-Shun Lee , Kirti H. Valia , Te-Yen Chien
- 申请人地址: NJ New Brunswick
- 专利权人: Rutgers, The State University of New Jersey
- 当前专利权人: Rutgers, The State University of New Jersey
- 当前专利权人地址: NJ New Brunswick
- 主分类号: A61K9/00
- IPC分类号: A61K9/00 ; A61K9/70 ; A61K31/565
摘要:
This invention relates to a novel transdermal absorption dosage unit comprising a backing layer, an adjoining layer of solid polymer matrix in which estradiol or another steroidal pharmaceutical having estrogenic activity is microdispersed; and a biologically acceptable adhesive means by which the dosage unit adheres to the skin of the subject being administered said estradiol or another said steroidal pharmaceutical and adapted to permit transdermal absorption of said estradiol or another said steroidal pharmaceutical. Additionally, the invention relates to improved estradiol or other estrogenic steroid maintenance therapy.
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