A differential amplifier includes first and second matched field-effect transistors (FETs) (21,22) having their source electrodes connected together and to a current source (2), and their drain electrodes connected respectively to an input and an output of a current mirror circuit (3). The FETs (21,22) are depletion-mode FETs, and the current source comprises parallel-connected third and fourth depletion-mode FETs (25,26) matched to the first and second FETs (21,22). The current source (2) and current mirror (3) act to constrain the first and second FETs (21,22), to operate over a predetermined operating curve, for which they are optimally matched to one another. The differential amplifier may be constructed as an integrated circuit, and may form part of a circuit for sensing current in a power semiconductor device.