发明授权
- 专利标题： Use of volume exclusion agents for the enhancement of in situ hybridization
- 专利标题（中）： 使用体积排阻剂来增强原位杂交
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申请号： US130709申请日： 1987-12-09
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公开(公告)号： US4886741A公开(公告)日： 1989-12-12
- 发明人: Dennis E. Schwartz
- 申请人： Dennis E. Schwartz
- 申请人地址： WA Bothel
- 专利权人： Microprobe Corporation
- 当前专利权人： Microprobe Corporation
- 当前专利权人地址： WA Bothel
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; C12Q1/70
摘要：
This invention relates to methods for using volume exclusion agents to enhance in situ hybridization rates between short oligonucleotide probes and their target polynucleotides where the cells containing the target polynucleotides are adhered onto a glass substrate. In one aspect, the invention specifically relates to the use of volume exclusion agents to facilitate assay and diagnostic procedures for the detection of a virus, such as human papillomavirus (HPV). In addition, diagnostic kits embracing the above methods are described herein.
公开/授权文献
- US5322492A Exercise apparatus 公开/授权日：1994-06-21
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