发明授权
US4889856A 7,8-dihydro-4-(1-pierazinyl)-6H-thiopyrano-[3,2-d] pyrimidines as
.beta.-blockers
失效
7,8-二氢-4-（1-吡嗪基）-6H-噻喃并[3,2-d]嘧啶作为β-阻断剂
- 专利标题： 7,8-dihydro-4-(1-pierazinyl)-6H-thiopyrano-[3,2-d] pyrimidines as .beta.-blockers
- 专利标题（中）： 7,8-二氢-4-（1-吡嗪基）-6H-噻喃并[3,2-d]嘧啶作为β-阻断剂
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申请号： US91471申请日： 1987-08-31
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公开(公告)号： US4889856A公开(公告)日： 1989-12-26
- 发明人: Richard L. Tolman , Arthur F. Wagner , John J. Baldwin , Adolph Pietruszkiewicz
- 申请人： Richard L. Tolman , Arthur F. Wagner , John J. Baldwin , Adolph Pietruszkiewicz
- 申请人地址： NJ Rahway
- 专利权人： Merck & Co., Inc.
- 当前专利权人： Merck & Co., Inc.
- 当前专利权人地址： NJ Rahway
- 主分类号： C07D495/04
- IPC分类号： C07D495/04
摘要：
7,8-Dihydro-4-(1-piperazinyl)-6H-thiopyranopyrimidines have .beta.-adrenergic blocking properties and are thus useful in the treatment of cardiovascular ailments known to be amenable to .beta.-blocker therapy. Certain of the compounds are useful in the treatment of elevated intraocular pressure by topical ocular administration.
公开/授权文献
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