发明授权
- 专利标题： Oligopeptidyl-5-fluorouridine compounds and process for preparing the same
- 专利标题（中）： 寡肽基5-氟尿苷化合物及其制备方法
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申请号： US148507申请日： 1988-01-29
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公开(公告)号： US4892939A公开(公告)日： 1990-01-09
- 发明人: Katsumi Sakai , Kiyoaki Chou , Takeshi Endo
- 申请人： Katsumi Sakai , Kiyoaki Chou , Takeshi Endo
- 申请人地址： JPX Toyama
- 专利权人： Fuji Kagaku Kogyo Kabushiki Kaisha
- 当前专利权人： Fuji Kagaku Kogyo Kabushiki Kaisha
- 当前专利权人地址： JPX Toyama
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; C07H19/06 ; C07K9/00
摘要：
New 5-fluorouridine compounds of the general formula: ##STR1## wherein n is an integer of 1 to 3, R' stands for a straight or branched chain alkyl group having 1 to 4 carbon atoms or a benzyl group, and R stands for an amino acid residue selected from the group consisting of alanyl, phenylalanyl, valyl, tyrosyl, 3,4-dihydroxyphenylalanyl and lysyl groups. These compounds possess excellent anti-malignant tumor, anti-viral and immunosuppressive activities.
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