For a process for the manufacture of powders from molten materials by atomizing the melt to particles by means of fluid media and cooling the particles as they fall, a melting chamber (3) is provided which has a melting system (4) disposed in the melting chamber (3) and an atomizing tower (8) is provided which is associated with the atomizing system (9) and attached to the melting chamber (3). For the production of powders of finest particle size with high purity and uniformity, a plurality of nozzles (11, 12, . . .) which can be aimed in their holders at the molten stream, are used for projecting a low-boiling liquefied gas under a pressure of 50 to 700 bar against the molten stream (23) entering the atomizing tower (8).