发明授权
- 专利标题： Purified interleukin 2
- 专利标题（中）： 纯化白细胞介素2
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申请号： US205423申请日： 1988-06-10
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公开(公告)号： US4925919A公开(公告)日： 1990-05-15
- 发明人: Roland Mertelsmann , Karl Welte , Salvatore Venuta
- 申请人： Roland Mertelsmann , Karl Welte , Salvatore Venuta
- 专利权人： Roland Mertelsmann,Karl Welte,Salvatore Venuta
- 当前专利权人： Roland Mertelsmann,Karl Welte,Salvatore Venuta
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; C07K14/55
摘要：
Interleukin 2 (IL 2; T-cell growth factor), produced with and without costimulation by Burkitt's lymphoma line Daudi, is highly purified approximately over 37,000-fold to apparent homogeneity from lymphocyte-conditioned medium derived from normal human blood cells by (NH.sub.4).sub.2 SO.sub.4 -precipitation, ion-exchange chromatogrThis invention was made with support in part under Grants CA 08748, CA 22507, CA 25608, CA 20194, CA 21525, CA31525, P01-CA-20194, AI 18 321-01, CA 23766 and CA 33050 awarded by the National Cancer Institute, National Institute of Health, DHEW. The government has certain rights in this invention.
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