发明授权
US4939156A New tetramethyl-cis-diaza-bicyclo{4.2.0}octane-3,5-dione derivatives
having differentiation-inducing activity and antiviral activity
失效
具有分化诱导活性和抗病毒活性的新的四甲基 - 顺 - 二氮杂双环{4.2.0}辛烷-3,5-二酮衍生物
- 专利标题: New tetramethyl-cis-diaza-bicyclo{4.2.0}octane-3,5-dione derivatives having differentiation-inducing activity and antiviral activity
- 专利标题(中): 具有分化诱导活性和抗病毒活性的新的四甲基 - 顺 - 二氮杂双环{4.2.0}辛烷-3,5-二酮衍生物
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申请号: US219200申请日: 1988-07-08
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公开(公告)号: US4939156A公开(公告)日: 1990-07-03
- 发明人: Motoo Hozumi , Tsuneo Itoh , Yoshio Honma , Norio Kawahara , Ichiro Ishikawa , Haruo Ogura
- 申请人: Motoo Hozumi , Tsuneo Itoh , Yoshio Honma , Norio Kawahara , Ichiro Ishikawa , Haruo Ogura
- 申请人地址: JPX
- 专利权人: Meiji Seika Kaisha, Ltd.
- 当前专利权人: Meiji Seika Kaisha, Ltd.
- 当前专利权人地址: JPX
- 优先权: JPX62-172091 19870711; JPX63-53817 19880309
- 主分类号: C07D239/70
- IPC分类号: C07D239/70 ; C07H19/06
摘要:
As new compounds are now provided 7,7,8,8,-tetramethyl-cis-diaza-bicyclo{4.2.0}octane-3,5,-dione derivatives which have an activity to induce the differentiation of tumor cells and are useful as antitumor agent, and which also have an antiviral activity against various viruses and are useful as antiviral agent. These new derivatives may be produced by a photo-addition reaction of a uracil compound with 2,3-dimethyl-2-butene.
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