Disclosed herein is a method for operating blast furnace, wherein, when charging coke and ore alternately from the furnace top to form alternate coke and ore layers for operation of a blast furnace, a coke layer is formed by charging coke of properties especially suitable for improvement of gas and liquid permeability of the coke layer to the central part thereof or an ore layer is formed by charging ordinary versatile type coke to the central part of the ore layer prior to formation thereof. The centrally charged coke forms a major part of the dead coke layer which is sequentially renewed under the cohesive zone of the blast furnace to maintain appropriate gas and liquid permeability of the dead coke layer, thereby enhancing the production efficiency and stability of the blast furnace operation while suppressing erosive wear of refractory walls of the furnace.