发明授权
US4966895A Cyclic monophosphates of purine and pyrimidine acyclonucleosides as
anti-retroviral agents
失效
作为抗逆转录病毒剂的嘌呤和嘧啶环己基核苷的环磷酸单磷酸酯
- 专利标题: Cyclic monophosphates of purine and pyrimidine acyclonucleosides as anti-retroviral agents
- 专利标题(中): 作为抗逆转录病毒剂的嘌呤和嘧啶环己基核苷的环磷酸单磷酸酯
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申请号: US305234申请日: 1989-02-02
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公开(公告)号: US4966895A公开(公告)日: 1990-10-30
- 发明人: Richard L. Tolman , Malcolm MacCoss
- 申请人: Richard L. Tolman , Malcolm MacCoss
- 申请人地址: NJ
- 专利权人: Merck & Co. Inc.
- 当前专利权人: Merck & Co. Inc.
- 当前专利权人地址: NJ
- 主分类号: A61K31/675
- IPC分类号: A61K31/675
摘要:
The present invention relates to a method for treating mammals having acquired immuno-deficiency syndrome (AIDS) or AIDS-related complex or who are infected with other retroviruses, which comprises the administration of a therapeutically effective amount of a cyclic monophosphate derivative of a purine or pyrimidine acyclonucleoside. Process for the preparation of such compounds and compositions containing such compounds as the active ingredient thereof are also disclosed.
公开/授权文献
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