发明授权
- 专利标题： Medicament formulation containing dihydropyridines and a process for its preparation
- 专利标题（中）： 含有二氢吡啶类的药物制剂及其制备方法
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申请号： US852584申请日： 1986-04-16
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公开(公告)号： US4976964A公开(公告)日： 1990-12-11
- 发明人: Klaus Schlossmann , Alfred Zembrod , Stanislav Kazda , Peter Serno , Bernd Klinksiek
- 申请人： Klaus Schlossmann , Alfred Zembrod , Stanislav Kazda , Peter Serno , Bernd Klinksiek
- 申请人地址： DEX Leverkusen
- 专利权人： Bayer Aktiengesellschaft
- 当前专利权人： Bayer Aktiengesellschaft
- 当前专利权人地址： DEX Leverkusen
- 优先权： DEX3515335 19850427
- 主分类号： C07D211/90
- IPC分类号： C07D211/90 ; A61K9/127 ; A61K31/44 ; A61P9/00 ; A61P9/08 ; A61P9/10
摘要：
In the parenteral administration of a dihydropyridine, the improvement which comprises administering the dihydropyridine in an aqueous medium of pH 3 to 8.5 having dispersed therein liposomes with an average diameter of 20-1000 nm, the liposome membrane containng the following constituents by weight:(a) a part of a dihydropyridine, and(b) 5-500 parts of lipids.The aqueous medium is storage stable and readily injectable.
公开/授权文献
- US5217802A Hydrophobic polymeric membrane composites 公开/授权日：1993-06-08
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