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发明授权
US4980356A 2-imino-6-polyfluoroalkoxybenzothiazole derivatives, and pharamaceutical compositions containing them and their treatment of medical conditions associated with the effects of glutamate 失效
2-亚氨基-6-多氟烷氧基苯并噻唑衍生物和含有它们的药物组合物及其与谷氨酸的作用相关的医学病症的治疗

2-imino-6-polyfluoroalkoxybenzothiazole derivatives, and pharamaceutical compositions containing them and their treatment of medical conditions associated with the effects of glutamate
摘要：
Compounds of formula: ##STR1## and their salts, in which R.sub.1 represents polyfluoroalkoxy, and R.sub.2 represents alkyl, alkenyl (3-6 C), [cycloalkyl (3-6 C)]-alkyl, carbamoylalkyl, dialkylcarbamoylalkyl, acylaminoalkyl, phenylthioalkyl, hydroxyalkyl, cyanoalkyl, sulphamoylethyl, N-alkylsulphamoylethyl, pyridylthioalkyl, pyridiylalkylthioalkyl, pyridylsulphinylalkyl, alkynyl (3-6 C), phenylsulphinylalkyl, halophenylthioalkyl, (2,2,2-trifluoroethylthio)alkyl, 2-dialkylaminopropyl, pyrimidinylsulphinylalkyl, pyridylalkylsulphinylalkyl, halophenylsulphinylalkyl or (2,2,2-trifluoroethylsulphinyl)alkyl are useful in the treatment of medical conditions associated with the effects of glutamate.
摘要（中）：

式（Ⅰ）化合物及其盐，其中R1代表多氟烷氧基，R2代表烷基，烯基（3-6C），[环烷基（3-6C）] - 烷基，氨基甲酰基烷基，二烷基氨基甲酰基烷基，酰基氨基烷基 苯基亚磺酰基烷基，卤代苯硫基烷基，（2,2,2-三氟乙硫基）烷基，2-二烷基氨基丙基，嘧啶基亚磺酰基烷基，吡啶基烷基亚磺酰基烷基，吡啶基亚磺酰基烷基， 卤代苯基亚磺酰基烷基或（2,2,2-三氟乙基亚磺酰基）烷基可用于治疗与谷氨酸的作用相关的医学病症。

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