发明授权
US4997755A HMG-CoA reductase inhibitors produced by Nocardia sp. (MA 6455)
失效
由诺卡氏菌属产生的HMG-CoA还原酶抑制剂 (MA 6455)
- 专利标题: HMG-CoA reductase inhibitors produced by Nocardia sp. (MA 6455)
- 专利标题(中): 由诺卡氏菌属产生的HMG-CoA还原酶抑制剂 (MA 6455)
-
申请号: US181877申请日: 1988-04-14
-
公开(公告)号: US4997755A公开(公告)日: 1991-03-05
- 发明人: Joanne M. Williamson , David Houck , Edward S. Inamine
- 申请人: Joanne M. Williamson , David Houck , Edward S. Inamine
- 申请人地址: NJ Rahway
- 专利权人: Merck & Co., Inc.
- 当前专利权人: Merck & Co., Inc.
- 当前专利权人地址: NJ Rahway
- 主分类号: C07D309/30
- IPC分类号: C07D309/30 ; C12P7/62 ; C12P17/06 ; C12N1/20 ; C12P7/02 ; C12P33/06
摘要:
A microbiological process is described for the preparation of 6-desmethyl-6-.beta.-hydroxymethyl and 6-desmethyl-6-.beta.-carboxylovastatin derivatives and 8-acyl analogs thereof.