发明授权
US5004750A Benzofuran and benzothoiphene derivatives, of tetrazole and
anti-hyperuricemia use thereof
失效
苯并呋喃和苯并噻吩衍生物，四唑和抗高尿酸血症的应用
- 专利标题： Benzofuran and benzothoiphene derivatives, of tetrazole and anti-hyperuricemia use thereof
- 专利标题（中）： 苯并呋喃和苯并噻吩衍生物，四唑和抗高尿酸血症的应用
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申请号： US280564申请日： 1988-12-06
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公开(公告)号： US5004750A公开(公告)日： 1991-04-02
- 发明人: Tsuyoshi Tomiyama , Akira Tomiyama , Koichi Kubota
- 申请人： Tsuyoshi Tomiyama , Akira Tomiyama , Koichi Kubota
- 申请人地址： JPX Nagano
- 专利权人： Kotobuki Seiyaku Company Limited
- 当前专利权人： Kotobuki Seiyaku Company Limited
- 当前专利权人地址： JPX Nagano
- 优先权： JPX57-182130 19821019
- 主分类号： A61K31/34
- IPC分类号： A61K31/34 ; A61K31/343 ; A61K31/38 ; A61K31/381 ; A61P7/10 ; A61P19/06 ; C07D307/80 ; C07D333/56 ; C07D333/60 ; C07D405/12
摘要：
A new series of benzofuran and benzothiophene derivatives are disclosed. These compounds have a structure which can be obtained by substituting the third position of 2-lower alkyl-benzofuran or 2-lower alkyl-benzothiophene with a substituted benzene derivative, itaconic acid derivative or a substituted phenoxymethyl tetrazole derivative. They are useful as diuretics without side effects of elevating serum uric acid levels and can be used in the treatment of hyperuricemia.
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