发明授权
US5051357A Method and assay using inactivation of factors Va and VIIIa by activated
Protein C to diagnose thrombic disease or assay for Protein C and kit
therefor
失效
通过活化的蛋白C使因子Va和VIIIa失活以诊断血栓疾病或蛋白C及其试剂盒的方法和测定法
- 专利标题： Method and assay using inactivation of factors Va and VIIIa by activated Protein C to diagnose thrombic disease or assay for Protein C and kit therefor
- 专利标题（中）： 通过活化的蛋白C使因子Va和VIIIa失活以诊断血栓疾病或蛋白C及其试剂盒的方法和测定法
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申请号： US396234申请日： 1989-08-21
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公开(公告)号： US5051357A公开(公告)日： 1991-09-24
- 发明人: Houria I. Hassouna
- 申请人： Houria I. Hassouna
- 申请人地址： MI East Lansing
- 专利权人： Board of Trustees operating Michigan State University
- 当前专利权人： Board of Trustees operating Michigan State University
- 当前专利权人地址： MI East Lansing
- 主分类号： C12Q1/56
- IPC分类号： C12Q1/56 ; G01N33/86
摘要：
A method and test kit for indirectly assaying for Protein C is described. The method uses tissue thrombomodulin/tissue factor (TTP) and calcium chloride to produce thrombin and activate Protein C to Protein Ca without fibrin formation and then allows time for Protein Ca to inactivate Factors Va and VIIIa. A deficient plasma has a decreased activated thromboplastin assay clotting time compared to a control plasma. The method and test kit is used to diagnose thrombic diseases.
公开/授权文献
- US5814890A Thin-type semiconductor package 公开/授权日：1998-09-29
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