发明授权
- 专利标题: Method for labeling antibodies with a metal ion
- 专利标题(中): 用金属离子标记抗体的方法
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申请号: US34003申请日: 1987-04-02
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公开(公告)号: US5053493A公开(公告)日: 1991-10-01
- 发明人: Koon Y. Pak , Richard T. Dean , Jeffrey A. Mattis
- 申请人: Koon Y. Pak , Richard T. Dean , Jeffrey A. Mattis
- 申请人地址: PA Malvern
- 专利权人: Centocor Cardiovascular Imaging Partners, L.P.
- 当前专利权人: Centocor Cardiovascular Imaging Partners, L.P.
- 当前专利权人地址: PA Malvern
- 主分类号: A61K51/10
- IPC分类号: A61K51/10
摘要:
A simple, rapid and efficient method for labelling sulfhydryl-containing antibodies or antibody fragments with Tc-99m, Rh-186, Rh-188, Rh-189 or Rh-191 is disclosed. Labeled antibodies produced by the method are useful for radio-immunodiagnostic and/or radio-therapeutic purposes.
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