发明授权
- 专利标题: Analgesic oxazolopyridine compounds
- 专利标题(中): 镇痛恶唑吡啶化合物
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申请号: US564033申请日: 1990-08-07
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公开(公告)号: US5061713A公开(公告)日: 1991-10-29
- 发明人: Gerald Guillaumet , Christine Flouzat , Jacqueline Bonnet
- 申请人: Gerald Guillaumet , Christine Flouzat , Jacqueline Bonnet
- 申请人地址: FRX Neuilly-sur-Seine
- 专利权人: Science et Organization
- 当前专利权人: Science et Organization
- 当前专利权人地址: FRX Neuilly-sur-Seine
- 优先权: FRX8910596 19890807
- 主分类号: A61K31/44
- IPC分类号: A61K31/44 ; A61K31/50 ; A61K31/505 ; A61K31/53 ; A61P25/04 ; C07D498/04
摘要:
Compound of general formula (I): ##STR1## in which: X, Y, Z and T each represent, independently of one another, a nitrogen atom, a --CH.dbd. group or a group CW, in which W represents a halogen atom or a lower alkyl or alkoxy group optionally substituted with one or more halogen atoms, such as a trifluoromethyl group, on condition that only one of them represents a nitrogen atom,Ra, Rb, Rc, Rd and Re represent, independently of one another, a hydrogen atom, a halogen atom or a lower alkyl or alkoxy group optionally substituted with one or more halogen atoms, such as a trifluoromethyl group,B represents a hydrogen atom and D a hydroxyl group, or B and D simultaneously represent an oxygen atom,n represents 1 or 2, andR.sub.1 represents a hydrogen atom, a linear or branched lower alkyl, linear or branched lower alkenyl, aryl or lower arylalkyl group or a cycloalkyl group having 3 to 7 carbon atoms, it being possible for each of the lower alkyl, lower alkenyl, aryl, lower arylalkyl and cycloalkyl groups to be substituted with one or more halogen atoms or a lower alkyl or alkoxy group optionally substituted with one or more halogen atoms, such as a trifluoromethyl group,their isomers, epimers and diastereoisomers, and addition salts with a pharmaceutically acceptable acidare useful in the treatment of pain.
公开/授权文献
- US5603733A Leather softening 公开/授权日:1997-02-18
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