发明授权
- 专利标题: .alpha.-1-antichymotrypsin, analogues and methods of production
- 专利标题(中): α-1抗胰凝乳蛋白酶,类似物和生产方法
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申请号: US370704申请日: 1989-06-23
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公开(公告)号: US5079336A公开(公告)日: 1992-01-07
- 发明人: Harvey Rubin , Zhi M. Wang
- 申请人: Harvey Rubin , Zhi M. Wang
- 申请人地址: PA Philadelphia
- 专利权人: The Trustees of the University of Pennsylvania
- 当前专利权人: The Trustees of the University of Pennsylvania
- 当前专利权人地址: PA Philadelphia
- 主分类号: A61K38/00
- IPC分类号: A61K38/00 ; C07K14/81
摘要:
The invention provides .alpha.-1-antichymotrypsin and protein preparations comprising human .alpha.-1-antichymotrypsin produced by E. coli cells transformed with a DNA sequence encoding human .alpha.-1-antichymotrypsin. The invention also provides methods for producing .alpha.-1-antichymotrypsin. The invention further provides analogues of .alpha.-1-antichymotrypsin that exhibit antichymotrypsin, anti-trypsin and anti-thrombin activity and methods of producing the analogues.
公开/授权文献
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