发明授权
US5079382A Process for the production of 3,4-epoxybutyrate and intermediate therefor
失效
生产3,4-环氧丁酸和其中间体的方法
- 专利标题： Process for the production of 3,4-epoxybutyrate and intermediate therefor
- 专利标题（中）： 生产3,4-环氧丁酸和其中间体的方法
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申请号： US617345申请日： 1990-11-23
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公开(公告)号： US5079382A公开(公告)日： 1992-01-07
- 发明人: Naoaki Taoka , Kenji Inoue , Shigeo Hayashi , Noboru Ueyama , Satomi Takahashi
- 申请人： Naoaki Taoka , Kenji Inoue , Shigeo Hayashi , Noboru Ueyama , Satomi Takahashi
- 申请人地址： JPX Osaka
- 专利权人： Kanegafuchi Chemical Industry Co., Ltd.
- 当前专利权人： Kanegafuchi Chemical Industry Co., Ltd.
- 当前专利权人地址： JPX Osaka
- 优先权： JPX1-305895 19891125
- 主分类号： C07C303/30
- IPC分类号： C07C303/30 ; C07C309/65 ; C07C309/66 ; C07C309/73 ; C07D303/40
摘要：
A 3,4-epoxybutyrate of the formula: ##STR1## wherein R.sup.1 is an alkyl or aralkyl group is efficiently prepared by a process comprising steps of:(a) reacting 3,4-dihydroxybutyronitrile of the formula: ##STR2## with a sulfonyl chloride of the formula: R.sup.2 --SO.sub.2 --Cl wherein R.sup.2 is an alkyl group or a phenyl group which may be substituted in the presence of a base to obtain a compound of the formula: ##STR3## (b) reacting the compound prepared in the step (a) with an alcohol of the formula: R.sup.1 --OH in the presence of an acid to obtain a compound of the formula: ##STR4## and (c) reacting the compound prepared in the step (b) with a base to obtain the 3,4-epoxybutyrate.