发明授权
US5089635A 11 .beta.-phenyl-gonanes, their manufacture and pharmaceutical
preparations containing them
失效
11（BETA）-PHENYL-GONANES，他们的制造和药物制剂
- 专利标题： 11 .beta.-phenyl-gonanes, their manufacture and pharmaceutical preparations containing them
- 专利标题（中）： 11（BETA）-PHENYL-GONANES，他们的制造和药物制剂
-
申请号： US827050申请日： 1986-02-07
-
公开(公告)号： US5089635A公开(公告)日： 1992-02-18
- 发明人: Gunter Neef , Sybille Beier , Walter Elger , David Henderson , Eckard Otto , Ralph Rohde
- 申请人： Gunter Neef , Sybille Beier , Walter Elger , David Henderson , Eckard Otto , Ralph Rohde
- 申请人地址： DEX Berlin and Bergkamen
- 专利权人： Schering Aktiengesellschaft
- 当前专利权人： Schering Aktiengesellschaft
- 当前专利权人地址： DEX Berlin and Bergkamen
- 优先权： DEX3504421 19850207; DEX3527517 19850729
- 主分类号： C07D319/06
- IPC分类号： C07D319/06 ; C07J1/00 ; C07J15/00 ; C07J21/00 ; C07J41/00 ; C07J53/00
摘要：
13-alkyl-11.beta.-phenyl-gonanes of general formula I ##STR1## wherein A and B together stand for an oxygen atom, a CH.sub.2 group or a second bond between carbon atoms 9 and 10,X is an oxygen atom or the hydroxyimino grouping N.about.OH,R.sub.1 is a straight-chained or branched, saturated or unsaturated alkyl radical with up to 8 carbon atoms, which contains the grouping ##STR2## with X as described above, R.sub.2 is a methyl or ethyl radical in the .alpha. or .beta. position,R.sub.9, R.sub.10, R.sub.11 and R.sub.12 each stand for a hydrogen atom, a hydroxy, alkyl, alkoxy or acyloxy group with 1 to 4 carbon atoms respectively or a halogen atom and R.sub.3 and R.sub.4 have a variety of meanings, have antigestagenic and antiglucocorticoid effects.
公开/授权文献
信息查询
