- 专利标题： Substituted 7-oxomitosanes
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申请号： US485360申请日： 1990-02-26
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公开(公告)号： US5097036A公开(公告)日： 1992-03-17
- 发明人: Dolatrai M. Vyas , Terrence W. Doyle , Richard A. Partyka
- 申请人： Dolatrai M. Vyas , Terrence W. Doyle , Richard A. Partyka
- 申请人地址： NY New York
- 专利权人： Bristol-Myers Company
- 当前专利权人： Bristol-Myers Company
- 当前专利权人地址： NY New York
- 主分类号： C07D487/14
- IPC分类号： C07D487/14
摘要：
The present invention provides novel mitomycin analogs containing a disulfide group and processes for the preparation thereof. These compounds are mitomycin A analogs in which the 7-alkoxy group bears an organic substituent incorporating a disulfide group. Mitomycin A is an antibiotic of established utility, and the 7-O-substituted mitosane analogs thereof have similar utility.
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