发明授权
- 专利标题： One-step cephalosporin C amidase enzyme
- 专利标题（中）： 一步CEPHOROSPORIN C AMIDASE ENZYME
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申请号： US372399申请日： 1989-06-27
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公开(公告)号： US5104800A公开(公告)日： 1992-04-14
- 发明人: Mark S. Crawford , David B. Finkelstein , John A. Rambosek
- 申请人： Mark S. Crawford , David B. Finkelstein , John A. Rambosek
- 申请人地址： NJ Rahway
- 专利权人： Merck & Co., Inc.
- 当前专利权人： Merck & Co., Inc.
- 当前专利权人地址： NJ Rahway
- 主分类号： C12N1/21
- IPC分类号： C12N1/21 ; C12N9/80 ; C12N15/55 ; C12P35/02 ; C12R1/11 ; C12R1/125
摘要：
A process for the one-step conversion of cephalosporin C and derivatives thereof to the corresponding 7-aminocephalosporanic acid and derivatives comprising treating said cephalosporin C and derivatives with a cephalosporin C amidase enzyme of a recited sequence, the DNA encoding said enzyme, and expression thereof in a suitable host, e.g., Bacillus species under the control of a suitable promoter.
公开/授权文献
- US5449067A Extension cord caddy 公开/授权日：1995-09-12
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