发明授权
- 专利标题: Heterocyclic derivatives, their preparation and medicinal products containing them
- 专利标题(中): 杂环衍生物,其制备和含有它们的药物
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申请号: US615670申请日: 1990-11-19
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公开(公告)号: US5114949A公开(公告)日: 1992-05-19
- 发明人: Claude Gueremy , Jean-Luc Malleron , Serge Mignani
- 申请人: Claude Gueremy , Jean-Luc Malleron , Serge Mignani
- 申请人地址: FRX Antony
- 专利权人: Rhone-Poulenc Sante
- 当前专利权人: Rhone-Poulenc Sante
- 当前专利权人地址: FRX Antony
- 优先权: FRX8915177 19891120; FRX8917164 19891226; FRX9007774 19900621
- 主分类号: C07D209/46
- IPC分类号: C07D209/46 ; A61K31/40 ; A61K31/403 ; A61K31/4035 ; A61K31/415 ; A61K31/4184 ; A61K31/425 ; A61K31/428 ; A61K31/47 ; A61K31/495 ; A61K31/496 ; A61P3/04 ; A61P25/18 ; A61P25/24 ; A61P25/26 ; A61P25/28 ; A61P25/30 ; A61P43/00 ; C07D209/92 ; C07D235/26 ; C07D275/06 ; C07D401/14 ; C07D403/06 ; C07D403/14 ; C07D417/06 ; C07D417/12 ; C07D417/14 ; C07D471/04 ; C07D471/06 ; C07D513/04 ; C07D513/06
摘要:
Compounds are disclosed of formula:R.sub.1 --(CH.sub.2).sub.n --Hetin which R.sub.1 represents a residue of formula ##STR1## X represents a hydrogen atom or an alkyl radical, Y represents a hydrogen atom or an alkyl or alkoxy radical,Z represents an alkyl radical,n is equal to 2 or 3,Het represents a substituted piperidino (substituted at the 4-position with a 1-indenylidene, 1-indenyl or 1-indanyl radical or with a chain --(CH.sub.2).sub.m --R.sub.2 or .dbd.CH--R.sub.2), substituted 1,2,3,6-tetrahydro-1-pyridyl (substituted at the 4-position with a chain --(CH.sub.2).sub.m --R.sub.2),m is equal to 1 or 2, andR.sub.2 represents an optionally substituted 2- or 3-indolyl radical, a 1- or 2-indanyl, 1- or 2-indenyl, an optionally substituted 1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indol-2-yl radical, a 1,2,3,4-tetrahydro-3-quinolyl radical, an optionally substituted 1,2,3,4-tetrahydro-2-naphthyl radical or a 1-indolyl radical, their preparation and medicinal products containing them.
公开/授权文献
- US5767100A Compounds and methods for making and using same 公开/授权日:1998-06-16