发明授权
US5116974A 3-carbalkoxyamino-5-aminoacyl-5H-dibenz[b,f]azepines, and methods for
making
失效
3-卡巴氧基氨基-5-氨基乙基-5H-二苯并（B，F）亚油酸酯及其制备方法
- 专利标题： 3-carbalkoxyamino-5-aminoacyl-5H-dibenz[b,f]azepines, and methods for making
- 专利标题（中）： 3-卡巴氧基氨基-5-氨基乙基-5H-二苯并（B，F）亚油酸酯及其制备方法
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申请号： US546590申请日： 1990-06-29
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公开(公告)号： US5116974A公开(公告)日： 1992-05-26
- 发明人: Helmut Wunderlich , Andreas Stark , Lothar Zenker , Dieter Lohmann , Hildegard Poppe , Reni Bartsch , Aleksandr P. Skoldinov , Natalja V. Kaverina , Anna N. Grizenko , Valentin V. Lyskovzev
- 申请人： Helmut Wunderlich , Andreas Stark , Lothar Zenker , Dieter Lohmann , Hildegard Poppe , Reni Bartsch , Aleksandr P. Skoldinov , Natalja V. Kaverina , Anna N. Grizenko , Valentin V. Lyskovzev
- 申请人地址： DEX Radebeul
- 专利权人： Arzneimittelwerk Dresden GmbH
- 当前专利权人： Arzneimittelwerk Dresden GmbH
- 当前专利权人地址： DEX Radebeul
- 优先权： DDX330174 19890630
- 主分类号： C07D223/24
- IPC分类号： C07D223/24 ; A61K31/55 ; A61P9/06 ; C07D223/26 ; C07D223/28
摘要：
New 3-carbalkoxyamino-5-aminoacyl-5H-dibenz[b,f]azepines and their pharmaceutically acceptable acid addition salts, and methods for their synthesis are described. These compounds are useful as antiarrhythmic agents in the treatment of heart disorders. The new compounds are made by reacting a 3-carbalkoxyamino-5-halogenacyl-5H-dibenz[b,f]azepines with an amine to form the desired target product, which can be optionally converted into its pharmaceutically acceptable acid addition salt.
公开/授权文献
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