发明授权
- 专利标题： Process for preparing antiviral antibiotic BU-3889V
- 专利标题（中）： 制备抗病毒抗生素BU-3889V的方法
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申请号： US624029申请日： 1991-03-11
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公开(公告)号： US5124150A公开(公告)日： 1992-06-23
- 发明人: Masataka Konishi , Mitsuaki Tsunakawa , Osamu Tenmyo , Takeo Miyaki , Toshikazu Oki
- 申请人： Masataka Konishi , Mitsuaki Tsunakawa , Osamu Tenmyo , Takeo Miyaki , Toshikazu Oki
- 申请人地址： NY New York
- 专利权人： Bristol-Myers Squibb Co.
- 当前专利权人： Bristol-Myers Squibb Co.
- 当前专利权人地址： NY New York
- 主分类号： C12P1/06
- IPC分类号： C12P1/06
摘要：
Production of an antiviral antibiotic complex, BU-3889V and its bioactive components A.sub.1, A.sub.2, A.sub.3, D.sub.1, D.sub.2 and D.sub.3, by fermentation of a BU-3889V producing strain of the new microorganism Amycolatopsis orientalis ATCC-53884 is disclosed. Complex BU-3889V is recovered and the components separated by the use of ion exchange chromatography techniques. The bioactive components are characterized by their physico-chemical characterizing properties. The products have been found to be effective to inhibit viruses including herpes simplex virus, human immunodeficiency virus (HIV) and influenza virus.