发明授权
US5128364A Pyrrolo[1,2-a]indole hydroxylamine derivatives as inhibitors of
leukotriene biosynthesis
失效
吡咯并[1,2-a]吲哚羟胺衍生物作为白三烯生物合成的抑制剂
- 专利标题： Pyrrolo[1,2-a]indole hydroxylamine derivatives as inhibitors of leukotriene biosynthesis
- 专利标题（中）： 吡咯并[1,2-a]吲哚羟胺衍生物作为白三烯生物合成的抑制剂
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申请号： US676632申请日： 1991-03-28
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公开(公告)号： US5128364A公开(公告)日： 1992-07-07
- 发明人: Yves Girard , Pierre Hamel
- 申请人： Yves Girard , Pierre Hamel
- 申请人地址： CAX Kirkland
- 专利权人： Merck Frosst Canada, Inc.
- 当前专利权人： Merck Frosst Canada, Inc.
- 当前专利权人地址： CAX Kirkland
- 主分类号： C07D487/04
- IPC分类号： C07D487/04
摘要：
Compounds having the formula I: ##STR1## are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis and allograft rejection and in preventing the formation of atherosclerotic plaques.
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