发明授权
US5128365A Compounds having glutathione peroxidase activity and use thereof
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具有GLUTATHIONE过氧化酶活性的化合物及其用途
- 专利标题: Compounds having glutathione peroxidase activity and use thereof
- 专利标题(中): 具有GLUTATHIONE过氧化酶活性的化合物及其用途
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申请号: US383189申请日: 1989-07-19
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公开(公告)号: US5128365A公开(公告)日: 1992-07-07
- 发明人: Abraham Spector , Stephen R. Wilson , Paul A. Zucker
- 申请人: Abraham Spector , Stephen R. Wilson , Paul A. Zucker
- 申请人地址: NY New York NY New York
- 专利权人: The Trustees of Columbia University in the City of New York,New York University
- 当前专利权人: The Trustees of Columbia University in the City of New York,New York University
- 当前专利权人地址: NY New York NY New York
- 主分类号: C07C391/02
- IPC分类号: C07C391/02
摘要:
The present invention provides compounds having glutathione peroxidase activity and, therefore, are effective glutathione peroxidase replacements. These compounds are useful as drugs for the prevention of cataracts and as anti-oxidants for H.sub.2 O.sub.2 and other peroxides. The present invention also provides methods and pharmaceutical compositions of the compound.
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