发明授权
- 专利标题： Amino acid derivatives which have renin inhibiting activity
- 专利标题（中）： 具有疝抑制活性的氨基酸衍生物
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申请号： US501694申请日： 1990-03-29
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公开(公告)号： US5140011A公开(公告)日： 1992-08-18
- 发明人: Quirico Branca , Hans P. Marki , Werner Neidhart , Henri Ramuz , Wolfgang Wostl
- 申请人： Quirico Branca , Hans P. Marki , Werner Neidhart , Henri Ramuz , Wolfgang Wostl
- 申请人地址： NJ Nutley
- 专利权人： Hoffmann-La Roche, Inc.
- 当前专利权人： Hoffmann-La Roche, Inc.
- 当前专利权人地址： NJ Nutley
- 优先权： CHX1290/89 19890405
- 主分类号： A61K31/16
- IPC分类号： A61K31/16 ; A61K38/00 ; A61P9/04 ; A61P9/12 ; C07C237/06 ; C07C271/20 ; C07C279/12 ; C07D231/12 ; C07D233/54 ; C07D233/58 ; C07D233/64 ; C07D277/22 ; C07D333/10 ; C07D401/12 ; C07K5/02 ; C07K5/065 ; C07K5/097
摘要：
The compounds of the formula ##STR1## wherein A, R.sup.1, R.sup.2, R.sup.3 and R.sup.4 have the significance given in claim 1, in the form of optically pure diastereomers, mixtures of diastereomers, diastereomeric racemates or mixtures of diastereomeric racemates as well as pharmaceutically usable salts thereof inhibit the activity of the natural enzyme renin and can accordingly be used in the form of pharmaceutical preparations in the control or prevention of high blood pressure and cardiac insufficiency.
公开/授权文献
- US5621971A Multi-purpose attachment for ladies' shaver 公开/授权日：1997-04-22
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