发明授权
US5141862A Method of purifying tpa or plasminogen activator using a tripeptide of
the formula: -X-Y-argininal wherein X and Y are selected from the group
consisting of pro,phe,trp and tyr
失效
使用下式的三肽纯化tpa或纤溶酶原激活物的方法：-X-Y-精氨酸，其中X和Y选自由pro，phe，trp和tyr组成的组
- 专利标题： Method of purifying tpa or plasminogen activator using a tripeptide of the formula: -X-Y-argininal wherein X and Y are selected from the group consisting of pro,phe,trp and tyr
- 专利标题（中）： 使用下式的三肽纯化tpa或纤溶酶原激活物的方法：-X-Y-精氨酸，其中X和Y选自由pro，phe，trp和tyr组成的组
-
申请号： US510333申请日： 1990-04-17
-
公开(公告)号： US5141862A公开(公告)日： 1992-08-25
- 发明人: Arun Patel , A. Hirotoshi Nishikawa
- 申请人： Arun Patel , A. Hirotoshi Nishikawa
- 申请人地址： PA Philadelphia
- 专利权人： SmithKline Beecham Corporation
- 当前专利权人： SmithKline Beecham Corporation
- 当前专利权人地址： PA Philadelphia
- 主分类号： C12N9/72
- IPC分类号： C12N9/72
摘要：
A method for purifying tPA or a plasminogen activator having an active site resembling that of tPA from an impure solution thereof which comprises contacting the impure solution with a solid support having bound thereto a tripeptide of the formula: -X-Y-argininal, wherein X and Y are amino acids selected from the group consisting of pro, phe, trp and tyr. The method is also used with a tripeptide of the formula: -phe-Y-argininal, wherein Y is selected from the group consisting of phe, pro, trp, tyr, val, ile and glu(PEA).
公开/授权文献
- US5616606A Oligopeptide antiretroviral agents 公开/授权日：1997-04-01
信息查询
