发明授权
- 专利标题: Process of enantiomeric separation of carbacephem intermediates
- 专利标题(中): 卡培膦中间体对映体分离方法
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申请号: US734394申请日: 1991-07-23
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公开(公告)号: US5142038A公开(公告)日: 1992-08-25
- 发明人: Christopher W. Doecke , Jeffrey N. Levy , Wayne D. Luke , Michael A. Staszak
- 申请人: Christopher W. Doecke , Jeffrey N. Levy , Wayne D. Luke , Michael A. Staszak
- 申请人地址: IN Indianapolis
- 专利权人: Eli Lilly and Company
- 当前专利权人: Eli Lilly and Company
- 当前专利权人地址: IN Indianapolis
- 主分类号: C07B57/00
- IPC分类号: C07B57/00 ; C07D405/06
摘要:
Enantiomerically pure .beta.-lactam intermediates of the formula (I) ##STR1## are isolated from a haloalkane solvent through precipitation with methyl-t-butyl ether or methanol. The products thus obtained are key intermediates in the synthesis of antibiotic aagents. The process is appropriate for large scale production.
公开/授权文献
- US5765822A Clamping apparatus for securely holding objects 公开/授权日:1998-06-16
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