发明授权
US5149703A Quinoline-substituted chromans and related compounds as leukotriene
antagonists
失效
喹啉取代的苯并二氢吡喃和相关化合物作为白三烯拮抗剂
- 专利标题: Quinoline-substituted chromans and related compounds as leukotriene antagonists
- 专利标题(中): 喹啉取代的苯并二氢吡喃和相关化合物作为白三烯拮抗剂
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申请号: US755906申请日: 1991-09-06
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公开(公告)号: US5149703A公开(公告)日: 1992-09-22
- 发明人: Cheuk K. Lau , Claude Dufresne
- 申请人: Cheuk K. Lau , Claude Dufresne
- 申请人地址: CAX Kirland
- 专利权人: Merck Frosst Canada, Inc.
- 当前专利权人: Merck Frosst Canada, Inc.
- 当前专利权人地址: CAX Kirland
- 主分类号: C07D215/18
- IPC分类号: C07D215/18 ; C07D405/12 ; C07D409/12
摘要:
Compounds having the formula I: ##STR1## are antagonists of the actions of leukotrienes. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection.
公开/授权文献
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