发明授权
- 专利标题： Method of inhibiting parasitic activity
- 专利标题（中）： 抑制寄生虫活性的方法
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申请号： US638709申请日： 1991-01-08
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公开(公告)号： US5151445A公开(公告)日： 1992-09-29
- 发明人: Joseph K. Welply , Steven P. Adams , Jeffrey I. Gordon
- 申请人： Joseph K. Welply , Steven P. Adams , Jeffrey I. Gordon
- 申请人地址： MO St. Louis
- 专利权人： Washington University
- 当前专利权人： Washington University
- 当前专利权人地址： MO St. Louis
- 主分类号： A01N37/36
- IPC分类号： A01N37/36 ; A61K31/19 ; A61K31/20 ; A61K31/215 ; A61K31/22 ; A61K31/23 ; A61P33/00 ; A61P33/02 ; C07C59/125 ; C07C59/60 ; C07C323/52 ; C07K1/00
摘要：
A method of inhibiting parasitic activity is disclosed in which the biosynthesis of the glycosyl phosphatidylinositol (GPI) anchor of said parasite is inhibited by incorporating into said GPI anchor an oxy-substituted fatty acid analog in place of myristate. The inhibitory compounds ar C.sub.13 and C.sub.14 fatty acids or alkyl esters thereof in which a methylene group normally in carbon position 4 to 13 of said fatty acid is replaced with oxygen.
公开/授权文献
- US5801800A Visual display system for display resolution enhancement 公开/授权日：1998-09-01
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