发明授权
- 专利标题： Biodegradable microspheres as a carrier for macromolecules
- 专利标题（中）： 可生物降解的微球作为大分子的载体
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申请号： US463008申请日： 1990-01-09
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公开(公告)号： US5160745A公开(公告)日： 1992-11-03
- 发明人: Patrick P. DeLuca , Frantisek Rypacek
- 申请人： Patrick P. DeLuca , Frantisek Rypacek
- 申请人地址： KY Lexington
- 专利权人： The University of Kentucky Research Foundation
- 当前专利权人： The University of Kentucky Research Foundation
- 当前专利权人地址： KY Lexington
- 主分类号： A61K9/16
- IPC分类号： A61K9/16
摘要：
A method for preparing biodegradable microspheres having a three-dimensional network in which biologically active macromolecular agents are physically entrapped therein. The microsphere is able to degrade and release the macromolecular agent at a controlled rate. The method involves emulsifying a vinyl derivative of a biodegradable hydrophilic polymer, a water-soluble monovinyl monomer and a biologically active macromolecule in water, and copolymerizing the biodegradable hydrophilic polymer and the water-soluble monovinyl monomer such that the biologically active macromolecule is entrapped therein.
公开/授权文献
- US5575539A Wheel rim for a motor vehicle and process for making same 公开/授权日：1996-11-19
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