A process for forming a buried contact (50) in a semiconductor device (20) which avoids etch damage to the substrate and forms a self-aligned, low resistance contact to a silicon substrate (22) is provided. After forming a contact opening (32) through overlying insulating and conducting layers (24, 28,30), a silicide region (40) is formed in the substrate at the contact surface (34) exposed by the contact opening (32). A refractory metal silicide which provides high etching selectivity to polysilicon is formed in the substrate at the contact surface (34) by either a blanket deposition of a refractory metal into the contact opening (32), or alternatively, by a selective deposition process using contact surface (34) as a nucleation site. In a preferred embodiment, a cobalt or tantalum silicide region (40) is formed in the substrate at the contact surface (34) and a conductive layer (42) is deposited and etched to form an interconnect (48) contacting the silicide region (40). The high etching selectivity obtainable between the conductive layer ( 42) and the silicide region (40) avoids damage to the substrate surface providing improved device performance.