发明授权
- 专利标题： Pyridoindole derivatives and processes for preparation thereof
- 专利标题（中）： 吡啶并吲哚衍生物及其制备方法
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申请号： US495119申请日： 1990-03-19
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公开(公告)号： US5173493A公开(公告)日： 1992-12-22
- 发明人: Masayuki Kato , Kiyotaka Ito , Hisashi Takasugi
- 申请人： Masayuki Kato , Kiyotaka Ito , Hisashi Takasugi
- 申请人地址： JPX Osaka
- 专利权人： Fujisawa Pharmaceutical Company, Ltd.
- 当前专利权人： Fujisawa Pharmaceutical Company, Ltd.
- 当前专利权人地址： JPX Osaka
- 优先权： GBX8822646 19880927; GBX8903044 19890210
- 主分类号： A61K31/435
- IPC分类号： A61K31/435 ; A61K31/437 ; A61P1/00 ; A61P1/04 ; A61P1/08 ; A61P3/04 ; A61P9/00 ; A61P9/04 ; A61P9/06 ; A61P9/08 ; A61P9/10 ; A61P11/02 ; A61P25/04 ; A61P25/18 ; A61P25/20 ; A61P25/22 ; A61P25/24 ; A61P25/26 ; A61P25/28 ; A61P43/00 ; C07D471/04
摘要：
The invention relates to compounds for treatment of nausea and vomiting, of the formula ##STR1## wherein R.sup.1 is hydrogen, lower alkyl, lower alkenyl or N,N-di(lower)alkylaminomethyl,R.sup.2 is hydrogen, lower alkyl or halogen,R.sup.3 is imidazolyl or pyridyl, each of which may have substituent(s) selected from lower alkyl and imino-protective group, andR.sup.4 is hydrogen, lower alkyl, lower alkenyl or hydroxy(lower)alkyl and R.sup.5 is hydrogen, hydroxy or lower alkanoyloxy, orR.sup.4 and R.sup.5 are linked together to form an additional bond,or a pharmaceutically acceptable salt thereof.
公开/授权文献
- US3983164A Phenyl alkyleneoxy phenyl alkanoic acid esters 公开/授权日：1976-09-28