发明授权
- 专利标题: Isocarbacyclin derivatives and their pharmaceutically acceptable salts thereof
- 专利标题(中): 异卡环林衍生物及其药学上可接受的盐
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申请号: US584493申请日: 1990-09-14
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公开(公告)号: US5175338A公开(公告)日: 1992-12-29
- 发明人: Atsuo Hazato , Toshio Tanaka , Noriaki Okamura , Kiyoshi Bannai , Seizi Kurozumi , Masaaki Suzuki , Ryoji Noyori
- 申请人: Atsuo Hazato , Toshio Tanaka , Noriaki Okamura , Kiyoshi Bannai , Seizi Kurozumi , Masaaki Suzuki , Ryoji Noyori
- 申请人地址: JPX Osaka
- 专利权人: Teijin Limited
- 当前专利权人: Teijin Limited
- 当前专利权人地址: JPX Osaka
- 优先权: JPX1-99470 19860501; JPX1-219117 19860919; JPX1-219118 19860919; JPX1-219119 19860919
- 主分类号: C07C405/00
- IPC分类号: C07C405/00
摘要:
An isocarbacyclin derivative represented by the following formula [VII'] ##STR1## wherein A represents, a hydrocarbylcarboxylate group, a carboxymethoxycarbonyl group, an amide group, an acyloxymethyl group or a hydroxymethyl group; R.sup.4 represents H, a methyl group or a vinyl group; R.sup.5 represents a (substituted)alkyl group, a phenyl group, a phenoxy group or a cycloalkyl group; R.sup.e22 and R.sup.e32 represent H or a hydroxyprotecting group; n is 0 or 1;and a pharmaceutically acceptable salt thereof.
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