发明授权
US5178845A Intimate mixture of calcium and phosphate sources as precursor to
hydroxyapatite
失效
钙和磷酸盐源的紧密混合作为羟基磷灰石的前体
- 专利标题: Intimate mixture of calcium and phosphate sources as precursor to hydroxyapatite
- 专利标题(中): 钙和磷酸盐源的紧密混合作为羟基磷灰石的前体
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申请号: US724859申请日: 1991-07-02
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公开(公告)号: US5178845A公开(公告)日: 1993-01-12
- 发明人: Brent R. Constantz , Bryan Barr , Kevin McVicker
- 申请人: Brent R. Constantz , Bryan Barr , Kevin McVicker
- 申请人地址: CA Mountain View
- 专利权人: Norian Corporation
- 当前专利权人: Norian Corporation
- 当前专利权人地址: CA Mountain View
- 主分类号: A61F2/00
- IPC分类号: A61F2/00 ; A61L24/00 ; A61L24/02 ; A61L27/24 ; A61L27/46 ; C01B25/32 ; C01B25/455
摘要:
Novel compositions are provided for the production of hydroxyapatite, where a dry mixture is provided which combines a calcium source and an acidic phosphate source, particularly monocalcium phosphate monohydrate or orthophosphoric acid crystals. These two are combined, optionally with other ingredients, with mechanical mixing, resulting in partial reaction or intimate combination to produce a product which requires less water for formation of a desired viscosity, has enhanced mechanical properties and is physiologically acceptable.