发明授权
- 专利标题： Method of preparing HIV protease inhibitors
- 专利标题（中）： 制备HIV蛋白酶抑制剂的方法
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申请号： US845520申请日： 1992-02-27
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公开(公告)号： US5188950A公开(公告)日： 1993-02-23
- 发明人: Suresh K. Balani , Harri G. Ramjit , Steven M. Pitzenberger , Michael S. Schwartz , Anthony Y. H. Lu
- 申请人： Suresh K. Balani , Harri G. Ramjit , Steven M. Pitzenberger , Michael S. Schwartz , Anthony Y. H. Lu
- 申请人地址： NJ Rahway
- 专利权人： Merck & Co., Inc.
- 当前专利权人： Merck & Co., Inc.
- 当前专利权人地址： NJ Rahway
- 主分类号： C07D295/092
- IPC分类号： C07D295/092
摘要：
Novel dipeptide isosteres are the biotransformed products after incubation with rat liver slices. They inhibit HIV protease, and are useful in the prevention or treatment of infection by HIV and the treatment of AIDS, either as compounds, pharmaceutically acceptable salts (when appropriate), pharmaceutical composition ingredients, whether or not in combination with other antivirals, anti-infectives, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described.
公开/授权文献
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