Invention Grant
- Patent Title: Process for the preparation of phenylacetic derivatives of thieno-pyridines
- Patent Title (中): 噻吩并吡啶的苯乙酸衍生物的制备方法
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Application No.: US677482Application Date: 1991-03-29
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Publication No.: US5189170APublication Date: 1993-02-23
- Inventor: Michel Bouisset , Joel Radisson
- Applicant: Michel Bouisset , Joel Radisson
- Applicant Address: FRX Paris
- Assignee: Sanofi
- Current Assignee: Sanofi
- Current Assignee Address: FRX Paris
- Priority: FRX8912787 19890929
- Main IPC: C07C51/00
- IPC: C07C51/00
Abstract:
Compounds of formula: ##STR1## in which R.sub.1 and R.sub.2 are hydrogen or halogen, are prepared by reacting an aldehyde of formula: ##STR2## with CHBr.sub.3 and KOH in a mixture of an inert solvent and water. Further an ester of compound (I) wherein R.sub.1 is H and R.sub.2 is 2-Cl is reacted with 4,5,6,7-tetrahydrothieno[3,2-c]pyridine to produce a compound of formula III: ##STR3## which is useful as a medicament.
Public/Granted literature
- US4623010A Tire bead protector device Public/Granted day:1986-11-18
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