发明授权
- 专利标题: Quinoline derivatives
- 专利标题(中): 喹啉衍生物
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申请号: US773432申请日: 1991-10-09
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公开(公告)号: US5190951A公开(公告)日: 1993-03-02
- 发明人: Hiroshi Hasegawa , Kazuo Isomae , Takeshi Kotsugai , Noriaki Shioiri , Kumiko Sekine , Naokata Taido , Susumu Sato , Tadayuki Kuraishi
- 申请人: Hiroshi Hasegawa , Kazuo Isomae , Takeshi Kotsugai , Noriaki Shioiri , Kumiko Sekine , Naokata Taido , Susumu Sato , Tadayuki Kuraishi
- 申请人地址: JPX Tokyo
- 专利权人: SS Pharmaceutical Co., Ltd.
- 当前专利权人: SS Pharmaceutical Co., Ltd.
- 当前专利权人地址: JPX Tokyo
- 优先权: JPX2-281093 19901019; JPX2-281094 19901019
- 主分类号: C07D219/06
- IPC分类号: C07D219/06 ; C07D221/16 ; C07D401/06 ; C07D471/04
摘要:
Quinoline derivatives of the formula, ##STR1## wherein > A represents a group >N--(CH.sub.2).sub.n --, >C.dbd., >C.dbd.CH(CH.sub.2).sub.n --, or >CH(CH.sub.2).sub.n --, wherein n is an integer of 0-7; Y represents a group >C.dbd.O or >CHOH, R.sup.1 is a hydrogen atom, a halogen atom, an alkyl group, an alkoxy group, or an alkylthio group, R.sup.2 is a hydrogen atom, a halogen atom, an alkyl group, a hydroxy group, an alkoxy group, a phenyl group which may have a substituent, a phenoxy group, an alkanoyloxy group, or an amino group which may have a substituent, R.sup.3 is a hydrogen atom, a halogen atom, an alkyl group, or an alkoxy group, and m is an integer of 1-3. The compounds and their salts exhibit a superior antiacetylcholinesterase activity with no side effects and are effective for the prevention or cure of senile dementia or memory disturbance.
公开/授权文献
- US5819814A Method and assembly for filling an anesthetic evaporator 公开/授权日:1998-10-13