发明授权
- 专利标题： Piperidinyl and piperazinyl derivatives
- 专利标题（中）： 哌啶基和哌嗪衍生物
-
申请号： US841922申请日： 1992-02-25
-
公开(公告)号： US5202346A公开(公告)日： 1993-04-13
- 发明人: John A. Butera , Jehan F. Bagli , John W. Ellingboe
- 申请人： John A. Butera , Jehan F. Bagli , John W. Ellingboe
- 申请人地址： NY New York
- 专利权人： American Home Products Corporation
- 当前专利权人： American Home Products Corporation
- 当前专利权人地址： NY New York
- 主分类号： C07D211/30
- IPC分类号： C07D211/30 ; C07D211/44 ; C07D295/192 ; C07D401/12
摘要：
Compounds of the formula: ##STR1## in which R.sup.1 is alkylsulfonamido of 1 to 6 carbon atoms, arylsulfonamido of 6 to 10 carbon atoms, --NO.sub.2,--CN, 1-imidazolyl or 1,2,4-triazol-1-yl;Y is ##STR2## --CH.sub.2 --, --O--, --S--, or --SO.sub.2 --; X is --CH.dbd. or --N.dbd.;R.sup.2 is hydrogen when n is 0, otherwise it is hydrogen or --OH;n is one of the integers 0, 1, 2, 3, 4, 5 or 6;A is ##STR3## where R.sup.3 is alkylsulfonamido of 1 to 6 carbons atoms, arylsulfonamido of 6 to 10 carbon atoms, --NO.sub.2, --CN, 1-imidazolyl or 1,2,4-triazol-1-yl; or ##STR4## where R.sup.4 is hydrogen or alkyl of 1 to 6 carbon atoms; with the provisos that;a) X is --CH.dbd. when Y is ##STR5## --O-- or --S-- and when Y is ##STR6## and R.sup.2 is --OH; b) X is --N.dbd. when A is ##STR7## c) A is ##STR8## when Y is --S-- or --SO.sub.2 -- and X is --CH.dbd., and their pharmaceutically acceptable salts are Class III antiarrhythmic agents.
公开/授权文献
- US06082316A Heat generator for vehicle heating system 公开/授权日：2000-07-04
信息查询
