发明授权
- 专利标题： Transmucosal formulations of low molecular weight peptide drugs
- 专利标题（中）： 低分子重量肽药物的转运配方
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申请号： US469443申请日： 1990-04-09
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公开(公告)号： US5204108A公开(公告)日： 1993-04-20
- 发明人: Lisbeth Illum
- 申请人： Lisbeth Illum
- 申请人地址： GBX Nottingham
- 专利权人： Danbiosyst UK Ltd.
- 当前专利权人： Danbiosyst UK Ltd.
- 当前专利权人地址： GBX Nottingham
- 优先权： GBX8723846 19871010
- 主分类号： A61K9/00
- IPC分类号： A61K9/00 ; A61K9/16 ; A61K9/50 ; A61K38/00 ; A61K38/22 ; A61K39/00
摘要：
A drug delivery composition comprising a plurality of microspheres and active drug associated with each microsphere, the drug being for systemic delivery and having a maximum molecular weight of 6000, and the composition being substantially free of an enhancer. The microspheres may be of starch, gelatin or albumin. Suitable drugs include peptides, such as insulin, and antigenic vaccine ingredients. The compositions are suitable for delivery across a mucosal surface such as the vagina, eye or nose.
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