发明授权
- 专利标题: Peptides having atrial natriuretic factor activity
- 专利标题(中): 具有心房利钠因子活性的肽
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申请号: US789378申请日: 1991-11-05
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公开(公告)号: US5204328A公开(公告)日: 1993-04-20
- 发明人: Ruth F. Nutt , Stephen F. Brady , Daniel F. Veber , Theresa M. Williams
- 申请人: Ruth F. Nutt , Stephen F. Brady , Daniel F. Veber , Theresa M. Williams
- 申请人地址: NJ Rahway
- 专利权人: Merck & Co., Inc.
- 当前专利权人: Merck & Co., Inc.
- 当前专利权人地址: NJ Rahway
- 主分类号: A61K38/00
- IPC分类号: A61K38/00 ; C07K14/58
摘要:
Atrial natriuretic factor analogs containing N-alkylated amino acids and showing enhanced potency and increased metabolic stability. These analogs have natriuretic, diuretic and vasorelaxant activity, making them suitable for treating congestive heart failure and renal hypertension.
公开/授权文献
- US5800522A Interior liner for tubes, pipes and blood conduits 公开/授权日:1998-09-01
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