发明授权
US5219564A Poly(alkylene oxide) amino acid copolymers and drug carriers and charged
copolymers based thereon
失效
聚(环氧烷)氨基酸共聚物和药物载体和基于其的带电共聚物
- 专利标题: Poly(alkylene oxide) amino acid copolymers and drug carriers and charged copolymers based thereon
- 专利标题(中): 聚(环氧烷)氨基酸共聚物和药物载体和基于其的带电共聚物
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申请号: US726301申请日: 1991-07-05
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公开(公告)号: US5219564A公开(公告)日: 1993-06-15
- 发明人: Samuel Zalipsky , Durgadas Bolikal , Aruna Nathan , Joachim B. Kohn
- 申请人: Samuel Zalipsky , Durgadas Bolikal , Aruna Nathan , Joachim B. Kohn
- 申请人地址: NJ South Plainfield
- 专利权人: Enzon, Inc.
- 当前专利权人: Enzon, Inc.
- 当前专利权人地址: NJ South Plainfield
- 主分类号: A61K47/30
- IPC分类号: A61K47/30 ; A61K47/48 ; A61K49/00 ; A61L15/26 ; A61L27/18 ; C08G63/685 ; C08G65/32 ; C08G69/10 ; C08G69/40 ; C08G69/44 ; C08G81/00 ; H01M6/18
摘要:
Copolymers of poly(alkylene oxides) and amino acids or peptide sequences are disclosed, which amino acids or peptide sequences have pendant functional groups that are capable of being conjugated with pharmaceutically active compounds for drug delivery systems and cross-linked to form polymer matrices functional as hydrogel membranes. The copolymers can also be formed into conductive materials. Methods are also disclosed for preparing the polymers and forming the drug conjugates, hydrogel membranes and conductive materials.
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