发明授权
- 专利标题: Quinoline derivatives, their production and use
- 专利标题(中): 喹啉衍生物,其生产和使用
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申请号: US587795申请日: 1990-09-25
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公开(公告)号: US5223513A公开(公告)日: 1993-06-29
- 发明人: Kanji Meguro , Hitoshi Ikeda
- 申请人: Kanji Meguro , Hitoshi Ikeda
- 申请人地址: JPX Osaka
- 专利权人: Takeda Chemical Industries, Ltd.
- 当前专利权人: Takeda Chemical Industries, Ltd.
- 当前专利权人地址: JPX Osaka
- 优先权: JPX1-262782 19891006; JPX1-322290 19891211
- 主分类号: A61K31/47
- IPC分类号: A61K31/47 ; A61P3/06 ; A61P9/10 ; C07C275/28 ; C07C275/38 ; C07D215/227 ; C07D215/38
摘要:
A quinoline derivative of the formula (I): ##STR1## wherein each phenyl ring of A, B and C can have one or more substituents, X is ##STR2## (R.sup.1 is a hydrogen atom or a lower alkyl group) or ##STR3## (R.sup.2 is a lower alkyl group or a lower alkoxy group), and n is 0 or 1, or its salt, which possesses an inhibitory action against acyl-CoA: cholesterol acyltransferase.
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